I. Introduction
II. Uses of Actiq (Fentanyl Citrate) 400mcg OTFC Lozenges
III. Dosage of Actiq (Fentanyl Citrate) 400mcg OTFC Lozenges
IV. Side Effects of Actiq (Fentanyl Citrate) 400mcg OTFC Lozenges
V. Precautions for Using Actiq (Fentanyl Citrate) 400mcg OTFC Lozenges
VI. Conclusion
I. Introduction
Actiq (Fentanyl Citrate) 400mcg OTFC Lozenges are a powerful opioid medication used to manage breakthrough cancer pain in opioid-tolerant patients. The drug is administered orally through a transmucosal delivery system, which involves placing the lozenge against the inside of the cheek. It is important to understand the uses, dosage, side effects, and precautions of Actiq to ensure its safe and effective use.
II. Uses of Actiq (Fentanyl Citrate) 400mcg OTFC Lozenges
Actiq is indicated for the management of breakthrough cancer pain in patients who are already receiving and tolerant to around-the-clock opioid therapy for their underlying persistent cancer pain. The drug works by binding to specific receptors in the central nervous system, which reduces the perception of pain. Actiq is different from other opioids in that it is a potent agonist at the mu-opioid receptor but does not activate other opioid receptors to the same degree.
III. Dosage of Actiq (Fentanyl Citrate) 400mcg OTFC Lozenges
Actiq is supplied as a lozenge on a handle that is intended to be sucked until dissolved. The drug is available in six dosage strengths ranging from 200mcg to 1600mcg. The dosage of Actiq should be individualized based on the patient’s medical condition, previous opioid use, and the intensity of their pain. The starting dose for Actiq is typically 200mcg, but the dose may need to be adjusted based on the patient’s response. The maximum dose of Actiq is 1600mcg, and the drug should not be used more frequently than once every four hours.
IV. Side Effects of Actiq (Fentanyl Citrate) 400mcg OTFC Lozenges
Like all opioid medications, Actiq can cause side effects. Common side effects of Actiq include nausea, vomiting, constipation, dizziness, and drowsiness. These side effects usually resolve as the patient becomes more tolerant to the drug. However, Actiq can also cause serious side effects, such as respiratory depression, which can be life-threatening. Risk factors for serious side effects include taking
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